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The mechanism of vitamin C promoting wound healing

2025-07-03

1.Promote collagen synthesis

Vitamin C is an essential substance for collagen synthesis. It catalyzes the conversion of proline and lysine into hydroxyproline and hydroxylysine through hydroxylation reaction, ensuring normal cross-linking of collagen fibers and enhancing the strength and toughness of wound tissue structure.

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2.Antioxidant and anti-inflammatory effects

Clearing free radicals: Neutralizing free radicals generated by oxidative stress at the wound site, reducing lipid peroxidation damage to the cell membrane, and lowering levels of inflammatory factors.

Inhibiting the risk of infection: Enhancing the activity of neutrophils and macrophages, and improving the immune system's ability to clear pathogens.

3.Accelerate vascular repair and granulation tissue formation

Promote endothelial cell proliferation and shorten hemostasis time.

Stimulate fibroblast differentiation and accelerate granulation tissue filling of wound defect areas.

Applicable scenarios and supplementary suggestions

Postoperative recovery: Supplementing with vitamin C after surgery can shorten the wound healing time and reduce scar hyperplasia.

Skin trauma: For open wounds such as burns and abrasions, vitamin C assists in repairing the epidermal and dermal structures.

Nutritional supplementation pathway:

Natural foods: Citrus fruits (oranges, lemons), kiwis, strawberries, and broccoli are rich in vitamin C.

Supplements: Patients with severe trauma or absorption disorders can take vitamin C tablets orally according to medical advice, with a recommended daily intake of no more than 2000 milligrams

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