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Kukonzekera njira ya HMB-Ca
2025-03-17
Njira 1:
Pogwiritsa ntchito 4-methyl-4-hydroxy-2-pentanone (diacetone alcohol) monga momwe zimakhalira, madzi monga zosungunulira, NaOBr amadzimadzi amadzimadzi amagwiritsidwa ntchito popanga halogenated reaction, kenako acidification ndi isobutanol m'zigawo. HMB asidi mu Tingafinye isobutanol mwachindunji mchere ndi Ca (OH) 2 kupeza β - hydroxy - β - methylbutyrate calcium. Njira imeneyi ali ndi ubwino mkulu mankhwala chiyero ndi otsika kuipitsa chilengedwe.
- Njira 2:1) Kuchita kwa glacial acetic acid, sulfuric acid, ndi H2O2, kutsatiridwa ndi vacuum distillation, kumapereka yankho la peracetic acid;
- 2) Sakanizani mankhwala omwe apezeka mu gawo 1) ndi mowa wa diacetone, onjezani methyl acetate ngati zosungunulira kuti muyankhe, kenako tsitsani ndikusonkhanitsa gawo la 70 ℃. Zotsalira pambuyo pa distillation ndi njira yothetsera β - hydroxy - β - methylbutyric acid;
- 3) Onjezani madzi ndi sodium hydroxide yankho ku zotsalira za distillation zomwe zapezeka mu gawo 2) kuti musinthe pH kukhala 6.0-7.0. Kutenthetsa ndi kusungunula osakaniza, ndiye sefa. Onjezani calcium chloride ku filtrate, yambitsani zomwe zimachitika, ndipo sinthani pH mpaka 6.5-7.0 kachiwiri kuti muchepetse β - hydroxy - β - methylbutyrate calcium. Sefa ndi kuumitsa kuti mupeze mankhwala