Muna 1832, chiremba wemakemikari wechiFrench Michel Eug è ne Chevreul akatanga kuwana creatine muskeletal muscle, iyo yakazonzi "Creatine" mushure mezwi rechiGiriki rokuti "Kreas" (nyama). Creatine inonyanya kuchengetwa munyama yetsandanyama, iyo inogona kuderedza kuneta kwetsandanyama uye kukakavara, kuwedzera kusimba kwetsandanyama, kuita kuti tsandanyama dzisimbe, kukurumidza kugadzirwa kweprotein mumuviri wemunhu, kuderedza cholesterol, lipids yeropa, uye shuga yeropa, kunonoka kuchembera, uye kuita basa kana simba richidiwa zvakanyanya. Nekuwedzera creatine, muviri wemunhu unogona kuwedzera creatine reserves, kuvandudza phosphocreatine mazinga mumamhasuru, uye kuwedzera kwenguva pfupi, yakakwirira-yakanyanya kurovedza muviri kuita. Tsvagiridzo yakaratidza kuti creatine supplement haingononoke kuneta kwemhasuru, kuvandudza simba rinoputika uye kutsungirira kwevatambi, asi zvakare kubatsira kukurudzira kukura kwemhasuru uye kupora, zvichiita kuti ive yekuwedzera inovaka muviri kune vanofarira kusimba uye vatambi.