Ngaphantsi kwemvelaphi ephindwe kabini yezehlo eziphezulu zezifo ezingapheliyo kunye nokuvuswa kolwazi lwezempilo lwesizwe, "i-intestinal revolution" eqhutywa yi-fiber yokutya ilungisa ngokuzolileyo ipateni yoshishino lwezempilo yehlabathi. Ngokutsho koMbutho wezeMpilo weHlabathi (i-WHO), malunga ne-75% yabantu behlabathi bajongene nokungonelanga kwefayibha yokutya, ngelixa i-fiber yemihla ngemihla yabahlali baseTshayina kuphela i-50% yexabiso elicetyiswayo (25-30g). Kule mfuno ingxamisekileyo, i-fiber yokutya enyibilikayo yamanzi ebizwa ngokuba yi-Polydextrose, kunye nemisebenzi yayo egqwesileyo ye-physiological kunye neemeko ezibanzi zokusetyenziswa, isuke kwibhubhoratri ukuya kwitafile kawonkewonke kwaye ibe "sesona sithako esiphezulu" apho uluntu lwezondlo kunye neshishini lokutya linika ingqalelo efanayo. Ngokusekelwe kubungqina besayensi, iimeko zeklinikhi kunye nokusebenza kwezoshishino, eli phepha libonisa ngokucacileyo indlela i-polyglucose enokunyusa ngayo ixabiso le-multi-dimensional yempilo ye-metabolic, ukuphuculwa kwe-immune kunye nokukhusela izifo ezingapheliyo ngokusebenzisa ukulawulwa kwe-intestinal microecological.

Okokuqala, ubungqina besayensi: Iindlela ezine zempilo ezingundoqo ze-polyglucose

I-Polyglucose yenziwe kwi-polymerization ye-glucose, i-sorbitol kunye ne-citric acid, kunye neyodwa i-1, i-6-glucoside bond chain chain kunye nesakhiwo sesebe esiyinkimbinkimbi siyinika iimpawu zokugaya kunye nokufunxa ngumzimba womntu, kodwa idlala indima ephambili kwi-gut "umlawuli ongabonakaliyo".

1. Impilo yamathumbu: ukusuka kwibhalansi ye-microbiota ukuya kwisithintelo somzimba sokuzivikelag

Iimpawu ze-prebiotic ze-polyglucose ziye zaqinisekiswa yi-European Union EFSA (i-European Food Safety Authority). Uphononongo lubonise ukuba lunokukhetha ukukhuthaza ukwanda kweebhaktheriya eziluncedo ezifana ne-bifidobacteria, iLactobacillus kwaye inqanda ukukhula kweebhaktheriya ze-pathogenic ezifana ne-Escherichia coli (i-Gut Microbes, i-2023).

Ifektri ye-short-chain fatty acid (SCFA) : i-intestinal flora ferment polyglucose ukuvelisa i-SCFA efana ne-butyric acid kunye ne-propionic acid, engaboneleli kuphela amandla kwiiseli zekholoni, kodwa inciphisa ixabiso le-pH yamathumbu kunye nokunciphisa i-ammonia toxoid yokufunxa. IZiko leSizwe lezeMpilo laseJapan lifumene ukuba ukutya kwansuku zonke kwe-10g ye-polyglucose kunokunyusa i-fecal butyric acid concentration nge-40% (uNxibelelwano lweNdalo, i-2022).

Ukulungiswa komqobo womzimba : I-SCFA ikhuthaza ukubonakaliswa kwe-intestinal mucosal compact junction protein ngokuvula i-G protein-coupled receptor (GPR43) kunye nokunciphisa umngcipheko wokuvuza kwamathumbu. Ulingo lweKlinikhi kwizigulane ezinezifo zesifo sofuba (IBD) lubonise ukuba emva kweeveki ze-6 ze-polyglucose supplementation, imilinganiselo ye-intestinal permeability (efana ne-serum connexin) yehla nge-35% (i-Clinical Nutrition, i-2023).

2. Ulawulo lweswekile yegazi: Isantya se-carb bump

I-Polyglucose inokulibazisa izinga lokukhupha isisu kwaye yenze ijeli encangathi kumathumbu amancinci, ukuthintela ukusasazwa kweglucose kudonga lwamathumbu. Ulingo oluphindwe kabini oluyimfama oluqhutywe yi-China Centre for Disease Control and Prevention kunye neYunivesithi yaseJiangnan yaqinisekisa ukuba i-5g ye-polyglucose intake ngaphambi kokutya kwizigulane ezinohlobo lwe-2 Diabetes yanciphisa i-glucose ephezulu yegazi nge-22% kunye nokwandisa ukuzwela kwe-insulin nge-18% kwiiyure ze-2 emva kokutya (Ukunyamekela kwesifo sikashukela, i-2024).

Ukumelana ne-starch synergistic effect : Kukutya okuphantsi kwe-GI, indibaniselwano ye-polyglucose kunye nesitashi esinganyangekiyo kunokuthintela ngakumbi umsebenzi we-α-amylase kunye nokwandisa ixesha lokukhutshwa kweglucose. I-Yili eshushu "ubisi lomhlobo weswekile kaShuhua" ithatha le fomyula kwaye ibe yimveliso edumileyo kwicandelo lentengiso yeswekile.

3. Ukungenelela kwe-lipid metabolism: "umlawuli wendalo" wempilo ye-cardiovascular ...

I-Polyglucose iyanciphisa i-serum iyonke i-cholesterol (TC) kunye ne-low-density lipoprotein (LDL) ngokufunxa i-bile acids kunye nokukhuthaza ukukhutshwa kwayo, ukunyanzela isibindi ukuba sisebenzise i-cholesterol ukwenza i-bile acids entsha. Uphando lwe-10,000-person cohort luxhaswa ngemali yi-American Heart Association (AHA) lufumene ukuba abantu abadla i-15g ye-polyglucose imihla ngemihla babenomngcipheko ophantsi we-31% weziganeko ze-cardiovascular (Circulation, 2023).

Ubungqina obutsha bokukhusela isibindi : Uvavanyo lwezilwanyana lubonisa ukuba i-polyglucose inokuthintela ukubonakaliswa kwe-fatty acid synthase (FAS), ukunciphisa i-lipid deposition kwisibindi, kwaye ibe nemiphumo enokuthi iphucule kwi-non-alcoholic fatty disease (NAFLD) (Journal of Nutritional Biochemistry, 2023).

4. Ulawulo lobunzima: "i-trigger esebenza ixesha elide" yeempawu zokuhlutha

I-Polydextrose ifunxa amanzi kwaye yanda esiswini, ivuselela i-receptors yomatshini ukubonisa ukuzala kwengqondo. Iimvavanyo eziqhutywe yiBritish Nutrition Society zibonise ukuba izifundo ezongeze i-10g ye-polyglucose kwisidlo sasekuseni zine-18% yeekhalori ezimbalwa kwisidlo sasemini kunye ne-27% yamanqaku alambileyo (British Journal of Nutrition, 2023). I-brand yolawulo lobunzima bamazwe ngamazwe i-Optifast isungule i-high-fiber food replacement powder kunye ne-polyglucose njengesithako sayo esingundoqo, esibambe i-30% yesabelo semarike yokutshintshwa kokutya kwehlabathi.

Umsebenzi woShishino: Ukuphumelela kwetekhnoloji ukusuka kwilabhoratri ukuya kwindawo yokusetyenziswa

Ukumelana nokushisa okuphezulu, ukunyibilika okuphezulu kunye nekhalori ephantsi (1kcal / g) iipropathi ze-polyglucose zenza ukuba ibe yisithuthi esifanelekileyo sokwenza izinto ezintsha kwishishini lokutya. Imarike ye-polyglucose yehlabathi kulindeleke ukuba ikhule ukusuka kwi-1.25 yeebhiliyoni zeedola ngo-2023 ukuya kwi-2.87 yeebhiliyoni zeedola ngo-2030 (i-12.4% CAGR), kunye ne-China ephuma njengeyona ndawo ikhula ngokukhawuleza kwimarike yengingqi (i-Grand View Research, i-2024).

1. Amatyala okuveliswa kokutya okusebenzayo

Uphuculo lweemveliso zobisi : Uluhlu lukaMengniu lwe "Guanyi Milk · Fiber +" longeze i-polyglucose kunye neLactobacillus plantarum, egxile kwimpembelelo ephindwe kabini "yokungakhuseleki kwamathumbu +", umthamo wokuthengisa udlule kwi-100 yezigidi kwinyanga yokuqala yoluhlu.

I-snack health : Oonomatse abathathu baqalise "uchungechunge lwe-crispy" lwe-cookies ene-fiber ephezulu, ethatha indawo ye-50% yeswekile kunye ne-polyglucose kwaye iqulethe i-fiber ye-5g kwipakethi enye, kunye neentengiso zonyaka ezingaphezulu kwe-200 yezigidi zeepakethi.

Isicelo esikhethekileyo sokutya kwezonyango : Nutricia "Ukutya okugqwesileyo Ukhethayo" umgubo ogcweleyo wesondlo somgubo, ngokusebenzisa i-polyglucose regulation uxinzelelo lwe-osmotic, ukunciphisa umngcipheko wezigulana zesifo sohudo, ukubhaliswa kokutya okukhethekileyo kwezonyango (TY-2023-012).

2. IMigaqo kunye neMigangatho yokuKhatshwa

I-China "Umgangatho weSizwe woKhuseleko lokuTya oLongezelelweyo lokuTya iPolyglucose" (GB 25541-2024) yaphunyezwa ngokusesikweni ngoJulayi 2024, icacisa ubunyulu bayo ≥99%, ikhokelela ≤0.2mg / kg kunye nezinye izibonakaliso, kwaye ngokuhambelana neKhomishoni yamazwe ngamazwe ye-CODEX Alimentarius (CODEX) isiseko sophuhliso lwemigangatho yesiseko somgangatho woshishino.

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Okwesithathu, ukuqonda kwabathengi: imfuno yezempilo eqhutywa yi-fission yentengiso

1. Ukwahlulahlula kwesihlwele kunye nophuhliso lwendawo

Uqoqosho lwesilivere : Kwingxaki yokuqunjelwa kwabantu abadala, uTomson Bihealth "Jianli multi-fiber powder" ngokungena kwesiteshi sekhemesti, ireyithi yokuthenga kwakhona ye-65%.

Isondlo sikamama nomntwana : UFeihe "Xingfeifan Zhuorui" umgubo wobisi wosana wongeze i-polyglucose, egxile "kubudlelwane bamathumbu + nophuhliso lobuchopho", isabelo sentengiso sikwinqanaba lokuqala kumgubo wobisi wasekhaya.

Isondlo sezemidlalo : Gcina i-ffit8 iqanjwe ngegama elithi "fibrin bar" ukuhlangabezana neemfuno zabantu bokuqina bokugcwalisa ikhadi lokulawula. Kukho ngaphezulu kwe-100,000 amanqaku anxulumene neNcwadi yeXiaored.

2. Unxibelelwano lwezeNzululwazi kunye nemfundo yabaThengi ...

Ukwakhiwa kwe-matrix ye-KOL : UGqirha we-Djing kunye nekhulu leengcali zezondlo baphehlelele "iNkqubo yokuVuswa kweFayibha", efikelele kubasebenzisi abangaphezu kwezigidi ezingama-50 ngokusasazwa kwesayensi yendlela "ye-gut-immune axis" yepolyglucose.

Inkcazo yeBango eliSebenzayo : ULawulo lukaRhulumente loLawulo lweeMakethi lufuna ukuba iimveliso ze-polyglucose ezibhalwe "ukunceda ukugcina umsebenzi oqhelekileyo wamathumbu" kufuneka unikeze ubuncinane ubungqina bekliniki obu-2, ukukhuthaza imboni ukusuka "kukuthengisa ingcamango" ukuya "kwintengiso yobungqina" inguqu.

Okwesine, imiceli mngeni kunye nekamva: decode isikhululo esilandelayo sokuthengisa itekhnoloji

1. Ukuphumelela kobuchwephesha bomqobo

Ukwenziwa ngokwezifiso kwemolekyuli : Ngobunjineli be-enzyme ukuguqula idigri yepolymerization yepolyglucose, ukuphuhlisa iimveliso ezikhethekileyo zokuqunjelwa (iqondo eliphantsi lepolymerization) okanye isifo seswekile (inqanaba eliphezulu lepolymerization).

Itekhnoloji ye-microencapsulation : Ukutshiza ukutshiza kusetyenziselwa ukungcwaba i-polyglucose ukusombulula ingxaki yokuzinza kwiziselo ezimuncu, kwaye yongezwa kwiindidi ezintsha ezinje ngamanzi ahlwahlwazayo kunye neziselo zeti ezisebenzayo.

2. Inguquko yeMveliso eZinzileyo

UTate & Lyle, umboneleli ophambili wehlabathi, utyala imali eyi-120 yezigidi zeerandi kwiziko le-biofanking esebenzisa i-biology yokwenziwa ukuguqula i-cornstarch ibe yi-polyglucose, ukunciphisa ukukhutshwa kwekhabhoni nge-70% xa kuthelekiswa neenkqubo eziqhelekileyo kunye nokufikelela kwiSiqinisekiso soZinzo lwaMazwe ngaMazwe (ISCC PLUS).

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Eyesihlanu, uluvo lwengcali: i-polyglucose "iminyaka elishumi yegolide"

UGqr. URobert Lustig (Ingcali yesifo seMetabolic, kwiYunivesithi yaseCalifornia, eSan Francisco):

"Ixabiso le-polyglucose alikho kuphela kwiipropati zayo ze-fiber, kodwa kunye nokulawulwa kwayo kwenethiwekhi ye-metabolic ye-systemic ngokusebenzisa i-gut flora. Kwiminyaka elishumi ezayo, isondlo somntu esisekelwe kwi-polyglucose siya kuphazamisa i-paradigm yokulawula isifo esingapheliyo."

Wang Xingguo (uSekela Sihlalo woMbutho waseTshayina weSondlo):

"I-gap ye-fiber yokutya yabahlali baseTshayina iphezulu njenge-15g / ngosuku, kwaye ukusetyenziswa kweshishini le-polyglucose kunika isisombululo esisebenzayo" kwi-fiber supplement yesizwe ". Silindele ukuba iinkampani ezininzi zendawo zenze impumelelo kwi-teknoloji yokulungiselela izinto eziluhlaza kunye nokunciphisa ukuxhomekeka kwabo kwizinto ezithunyelwa ngaphandle."

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Isiphelo ...

Ukusuka ekuphuculeni i-microecology yamathumbu ekunciphiseni umngcipheko wezifo ezingapheliyo, i-polyglucose ihlaziya indawo yempilo yabantu ngendlela "egudileyo kwaye ithule." Ngokunzulu kophando lwezenzululwazi kunye nokuphindaphindwa kobuchwephesha bemizi-mveliso, olu tshintsho lwezempilo luqhutywa kukuveliswa kwezinto ezintsha zemolekyuli kunokusikhokelela kwixesha elitsha lempilo yesizwe "ngethumbu njenge-axis".

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http://www.jvvw.cn/polydextrose-water-soluble-dietary-fiber-product/